clinical trial methodology
Daily Alchemy: Can we make this controversy good?
26d ago“Should EMA’s virtual control group proposal replace randomized control arms in pivotal trials?”
Why can't anyone agree on a healthy diet?: Evidence-based medicine
The dropout problem In 2013, Stanford published a meta-analysis of 135 dietary trials. The headline: no difference between low-fat and low-carb at twelve months. The buried finding: the average dropout rate across all 135 trials was 40 percent.... Are psychedelics actually medicine?: Cautious researchers
The pattern In 1995, Purdue submitted trial data showing OxyContin had less abuse potential. The FDA approved it. Doctors wrote 80 million prescriptions....