How is AI being used in legit positively transformative ways?

I'm curious to hear about folding proteins, curing cancer, or personal examples like a recent I heard from @brian of Claude helping him get better at yoga.

My feed is mostly filled with things that feel like unconscious optimization processes run amok. More AI marketing slop, selling AI tools to be better at marketing AI tools, and weird recursions like that, and I'd love to get more of the optimistic, positive alternatives.